Due to the rapid and diverse growth of engineered nanomaterials (NMs), it is difficult for regulators and risk assessors to understand the potential for exposure to nanomaterials and whether methods used for assessing risk of conventional chemicals can be used for nanomaterials. The U.S. Food and Drug Administration (FDA) has finalized guidelines on the evaluation and use of NMs in FDA-regulated products. These guidelines focus on assessing safety, effectiveness and quality of products containing NMs. Many NMs are also regarded as “chemical substances” under the Toxic Substances Control Act (TSCA). Whereas, NMs that are used as pesticides are subject to the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) regulations.
Physicochemical characterisation (Cosmetics)
The ames test for mutagenicity
Environmental fate and behavior endpoints