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Ecotoxicology

The impact of different chemicals on the environment is a great cause of concern globally and raises evermore complex regulatory questions. The requirement of sophisticated test systems, instrumentation and scientific talent is crucial to address these concerns and develop feasible solutions.

Our highly experienced Study Directors are supported by well-trained technicians to maintain the diverse facilities and conduct extensive ecotoxicology studies. Constant in-house analytical support is available to our aquatic and terrestrial ecotoxicology studies via our state-of-the-art analytical laboratory. Intox is situated amidst the abundant nature, scenic lush-green beauty surrounded by enchanting agriculture hilltops of western ghats provides more suitable environmental resources for studies like bee/Lemna etc.

 

Aquatic

Comprehensive aquatic ecotoxicology data is necessary for regulatory submissions of agrochemicals, industrial chemicals and also for human and veterinary pharmaceuticals during Environmental Risk/Impact Assessments (ERA and EIA). We offer a range of aquatic ecotoxicology tests.

  • Growth inhibition test (algae OECD-201; Lemna- OECD 221)
  • Acute Immobilisation Test (Daphnia-OECD-202: Chironomus- OECD-235)
  • Fish- Acute (Guppy/carp, Rainbow trout, Zebrafish- OECD-203)
  • Fish Embryo Acute Toxicity (Zebrafish-OECD 236)
  • Reproduction Test (Daphnia Magna- OECD 211; Fish – OECD 229; Lymnaea stagnalis- OECD 243)
  • Fish, Short-term Toxicity Test on Embryo and Sac-Fry Stages (OECD 212)
  • Fish, Prolonged Toxicity Test: 14-Day Study (OECD 204)
  • Fish, Early-life Stage Toxicity Test (OECD 210)
  • Fish- Juvenile Growth Test (OECD 215)
  • Lumbriculus Toxicity Test (OECD 225)
  • Myriophyllum spicatum toxicity test (OECD 238)
  • Sediment-Water Toxicity Test-Chironomid (OECD 218/219)
  • Fish Cell Line Acute Toxicity: The RTgill-W1 cell line assay (OECD  249)

Terrestrial

Diversity of terrestrial organisms – plants, invertebrates and vertebrates – living in and on the soil makes hazard assessment of a chemical on a terrestrial environment critical and more complex. Our terrestrial ecotoxicology tests include:

  • Avian (Dietary, Acute oral- OECD-205; OECD-223)
  • Earthworm- (Acute- OECD-207; Reproduction – OECD 222)
  • Earthworm Subchronic Toxicity Test (OCSPP 850.3100)
  • Honeybee Acute Toxicity (Oral- OECD-213; Contact- OECD-214)
  • OECD-237 – Honeybee Larval Toxicity Test-Single Exposure
  • OECD 245 – Honeybee Chronic Oral Toxicity Test
  • Bumble Bee Acute Toxicity (contact OECD 246; oral OECD 247)
  • Reproduction Test (Avian-OECD 206; Enchytraeid- OECD 220; Collembolan – OECD 232; Potamopyrgus antipodarum- OECD 242)
  • Field testing for pollinators (Bee – Semi-field / Field studies- OPPTS 850.3040)
  • Bee brood feeding Bee – Semi-field / Field studies (OECD No 75, EPPO Standard PP1/170 (4)
  • Non-target Arthropod Studies; glass plate tests with Aphidius rhopalosiphi and Typhlodromus pyri (IOBC/WPRS 2000, 2009, EPPO guideline 170).
  • Non-target Plant Studies (Greenhouse, Field/semi-Field)

Soil microorganisms: Nitrogen and Carbon Transformation Test